Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D]' and Ligand = 'BDBM16948'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM16948 ((3Z)-5-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]p...) Show SMILES N[C@H](COc1cncc(c1)-c1ccc2NC(=O)\C(=C/c3c[nH]c4ccccc34)c2c1)Cc1c[nH]c2ccccc12 |r| Show InChI InChI=1S/C33H27N5O2/c34-24(11-22-16-36-30-7-3-1-5-26(22)30)19-40-25-12-21(15-35-18-25)20-9-10-32-28(13-20)29(33(39)38-32)14-23-17-37-31-8-4-2-6-27(23)31/h1-10,12-18,24,36-37H,11,19,34H2,(H,38,39)/b29-14-/t24-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	153	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem Lett 16: 3424-9 (2006) Article DOI: 10.1016/j.bmcl.2006.04.005 BindingDB Entry DOI: 10.7270/Q2K072JJ
					More data for this Ligand-Target Pair