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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAC-beta serine/threonine-protein kinase' and Ligand = 'BDBM24871'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RAC-beta serine/threonine-protein kinase


(Homo sapiens (Human))		BDBM24871
PNG
(2-acetamido-N-[1-({4-[2-(methylsulfanyl)-6-phenylp...)
Show SMILES CSc1ncc2cc(-c3ccccc3)c(nc2n1)-c1ccc(CN2CCC(CC2)NC(=O)CNC(C)=O)cc1
Show InChI InChI=1S/C30H32N6O2S/c1-20(37)31-18-27(38)33-25-12-14-36(15-13-25)19-21-8-10-23(11-9-21)28-26(22-6-4-3-5-7-22)16-24-17-32-30(39-2)35-29(24)34-28/h3-11,16-17,25H,12-15,18-19H2,1-2H3,(H,31,37)(H,33,38)
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Article
PubMed
n/an/a 5.13E+3n/an/an/an/an/an/a



Merck Research Laboratories



Assay Description
Purified recombinant human Akt kinase was monitored for kinase activity in the presence or absence of inhibitors in a 96-well format. Detection was d...

Bioorg Med Chem Lett 18: 1274-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.054
BindingDB Entry DOI: 10.7270/Q2G73C02
More data for this
Ligand-Target Pair