Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAC-beta serine/threonine-protein kinase' and Ligand = 'BDBM24897'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human))	BDBM24897 (1-[1-({4-[3-phenyl-5-(1H-1,2,4-triazol-3-yl)pyridi...) Show SMILES Nc1ncnc2n(ncc12)C1CCN(Cc2ccc(cc2)-c2ncc(cc2-c2ccccc2)-c2nnc[nH]2)CC1 Show InChI InChI=1S/C30H28N10/c31-28-26-16-37-40(30(26)35-18-33-28)24-10-12-39(13-11-24)17-20-6-8-22(9-7-20)27-25(21-4-2-1-3-5-21)14-23(15-32-27)29-34-19-36-38-29/h1-9,14-16,18-19,24H,10-13,17H2,(H2,31,33,35)(H,34,36,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	101	n/a	n/a	n/a	n/a	7.5	22
Merck Research Laboratories					Assay Description Purified recombinant human Akt kinase was monitored for kinase activity in the presence or absence of inhibitors in a 96-well format. Detection was d...				Bioorg Med Chem Lett 18: 2194-7 (2008) Article DOI: 10.1016/j.bmcl.2007.12.040 BindingDB Entry DOI: 10.7270/Q2BG2M8B
					More data for this Ligand-Target Pair