BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAC-gamma serine/threonine-protein kinase' and Ligand = 'BDBM50398357'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RAC-gamma serine/threonine-protein kinase


(Homo sapiens (Human))		BDBM50398357
PNG
(CHEMBL2177362)
Show SMILES C[C@@H]1C[C@@H](O)c2ncnc(N3CCN(CC3)C(=O)[C@H](CNC3CCOCC3)c3ccc(Cl)c(F)c3)c12 |r|
Show InChI InChI=1S/C26H33ClFN5O3/c1-16-12-22(34)24-23(16)25(31-15-30-24)32-6-8-33(9-7-32)26(35)19(14-29-18-4-10-36-11-5-18)17-2-3-20(27)21(28)13-17/h2-3,13,15-16,18-19,22,29,34H,4-12,14H2,1H3/t16-,19-,22-/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 12n/an/an/an/an/an/a



Array BioPharma Inc.

Curated by ChEMBL


Assay Description
Competitive inhibition of wild-type full-length amino-terminal polyhistidine-tagged human Akt3 expressed in recombinant baculovirus system using fluo...

J Med Chem 55: 8110-27 (2012)


Article DOI: 10.1021/jm301024w
BindingDB Entry DOI: 10.7270/Q20P1160
More data for this
Ligand-Target Pair