Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM333700'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM333700 (1-(4- methoxy-3- (trifluoromethyl) phenyl)-3-(3-(6...) Show SMILES COc1ccc(NC(=O)Nc2cccc(Oc3ncnc4cc(OCCN5CCOCC5)c(OC)cc34)c2)cc1C(F)(F)F Show InChI InChI=1S/C30H30F3N5O6/c1-40-25-7-6-20(15-23(25)30(31,32)33)37-29(39)36-19-4-3-5-21(14-19)44-28-22-16-26(41-2)27(17-24(22)34-18-35-28)43-13-10-38-8-11-42-12-9-38/h3-7,14-18H,8-13H2,1-2H3,(H2,36,37,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<250	n/a	n/a	n/a	n/a	n/a
AMBIT BIOSCIENCES CORPORATION US Patent					Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....				US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC
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