Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM50172058'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Mus musculus)	BDBM50172058 (CHEMBL3805675) Show SMILES COc1cccc(c1)C1CC(=NN1c1ccccc1)c1ccc2OCCOc2c1 |c:11| Show InChI InChI=1S/C24H22N2O3/c1-27-20-9-5-6-18(14-20)22-16-21(25-26(22)19-7-3-2-4-8-19)17-10-11-23-24(15-17)29-13-12-28-23/h2-11,14-15,22H,12-13,16H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.28E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of mouse c-Raf assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr before MEK1 ad...				Bioorg Med Chem 24: 3052-3061 (2016) Article DOI: 10.1016/j.bmc.2016.05.012 BindingDB Entry DOI: 10.7270/Q2HX1FKZ
					More data for this Ligand-Target Pair