Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM50340279'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50340279 (CHEMBL1760639 | N-(6-(2-(3-(5-methyl-2-(2-(methyla...) Show SMILES CNCCOc1ccc(C)cc1NC(=O)NCCc1ccc2nc(NC(C)=O)[nH]c2c1 Show InChI InChI=1S/C22H28N6O3/c1-14-4-7-20(31-11-10-23-3)19(12-14)28-22(30)24-9-8-16-5-6-17-18(13-16)27-21(26-17)25-15(2)29/h4-7,12-13,23H,8-11H2,1-3H3,(H2,24,28,30)(H2,25,26,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono Curated by ChEMBL					Assay Description Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation counting				Bioorg Med Chem Lett 21: 2264-9 (2011) Article DOI: 10.1016/j.bmcl.2011.02.108 BindingDB Entry DOI: 10.7270/Q2MS3T23
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