Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM50344543'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50344543 (4-(2-(3-isopropylphenylamino)benzo[d]oxazol-5-ylox...) Show SMILES CNC(=O)c1cc(Oc2ccc3oc(Nc4cccc(c4)C(C)C)nc3c2)ccn1 Show InChI InChI=1S/C23H22N4O3/c1-14(2)15-5-4-6-16(11-15)26-23-27-19-12-17(7-8-21(19)30-23)29-18-9-10-25-20(13-18)22(28)24-3/h4-14H,1-3H3,(H,24,28)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISA				Bioorg Med Chem Lett 21: 3286-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.023 BindingDB Entry DOI: 10.7270/Q2R78FH0
					More data for this Ligand-Target Pair