Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RNA-directed RNA polymerase' and Ligand = 'BDBM50142743'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50142743 ((E)-6-[1-(4-Methoxy-benzyl)-1H-pyrrol-2-yl]-2,4-di...) Show SMILES COc1ccc(Cn2cccc2C=CC(=O)CC(=O)C(O)=O)cc1 |w:13.14| Show InChI InChI=1S/C18H17NO5/c1-24-16-8-4-13(5-9-16)12-19-10-2-3-14(19)6-7-15(20)11-17(21)18(22)23/h2-10H,11-12H2,1H3,(H,22,23)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	7.5	n/a
University of Rome La Sapienza Curated by ChEMBL					Assay Description Inhibitory concentration against NS5B HCV polymerase using [alpha-32P]UTP as radioligand (30 degree C for 2 h, at pH 7.5 with Tris-HCl buffer)				J Med Chem 48: 6304-14 (2005) Article DOI: 10.1021/jm0504454 BindingDB Entry DOI: 10.7270/Q2T43SNM
					More data for this Ligand-Target Pair