Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RNA-directed RNA polymerase' and Ligand = 'BDBM50181735'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181735 (5-(5-[2-chloro-5-(trifluoromethyl)phenyl]-furan-2-...) Show SMILES FC(F)(F)c1ccc(Cl)c(c1)-c1ccc(C=C2SC(=S)N(NS(=O)(=O)c3ccccc3)C2=O)o1 |w:15.15| Show InChI InChI=1S/C21H12ClF3N2O4S3/c22-16-8-6-12(21(23,24)25)10-15(16)17-9-7-13(31-17)11-18-19(28)27(20(32)33-18)26-34(29,30)14-4-2-1-3-5-14/h1-11,26H	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5b RNA polymerase				J Med Chem 49: 1034-46 (2006) Article DOI: 10.1021/jm050859x BindingDB Entry DOI: 10.7270/Q2CJ8D3W
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