Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RNA-directed RNA polymerase' and Ligand = 'BDBM50181945'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181945 (1-cyclopentyl-2-(4-(pyridin-4-ylmethoxy)phenyl)-1H...) Show SMILES OC(=O)c1ccc2n(C3CCCC3)c(nc2c1)-c1ccc(OCc2ccncc2)cc1 Show InChI InChI=1S/C25H23N3O3/c29-25(30)19-7-10-23-22(15-19)27-24(28(23)20-3-1-2-4-20)18-5-8-21(9-6-18)31-16-17-11-13-26-14-12-17/h5-15,20H,1-4,16H2,(H,29,30)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b NS5B RNA dependent RNA polymerase				Bioorg Med Chem Lett 16: 1859-63 (2006) Article DOI: 10.1016/j.bmcl.2006.01.032 BindingDB Entry DOI: 10.7270/Q2BK1BX6
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