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Found 1 hit Enz. Inhib. hit(s) with Target = 'Rap guanine nucleotide exchange factor 4' and Ligand = 'BDBM50098709'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Rap guanine nucleotide exchange factor 4


(Mus musculus)		BDBM50098709
PNG
(CHEMBL3593338)
Show SMILES CC(C)(C)c1cc(no1)C(=O)C(=N\Nc1ccc(F)c(Cl)c1)\C#N
Show InChI InChI=1S/C16H14ClFN4O2/c1-16(2,3)14-7-12(22-24-14)15(23)13(8-19)21-20-9-4-5-11(18)10(17)6-9/h4-7,20H,1-3H3/b21-13+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.70E+3n/an/an/an/an/an/a



University of Texas Medical Branch

Curated by ChEMBL


Assay Description
Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assay

J Med Chem 58: 6033-47 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00635
BindingDB Entry DOI: 10.7270/Q29025JD
More data for this
Ligand-Target Pair