Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rap guanine nucleotide exchange factor 4' and Ligand = 'BDBM50098723'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rap guanine nucleotide exchange factor 4 (Mus musculus)	BDBM50098723 (CHEMBL3594323) Show SMILES CCOC(=O)c1cccc(N\N=C(/C#N)C(=O)c2cc(on2)C(C)(C)C)c1 Show InChI InChI=1S/C19H20N4O4/c1-5-26-18(25)12-7-6-8-13(9-12)21-22-15(11-20)17(24)14-10-16(27-23-14)19(2,3)4/h6-10,21H,5H2,1-4H3/b22-15+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assay				J Med Chem 58: 6033-47 (2015) Article DOI: 10.1021/acs.jmedchem.5b00635 BindingDB Entry DOI: 10.7270/Q29025JD
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