Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rap guanine nucleotide exchange factor 4' and Ligand = 'BDBM50175272'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50175272 (CHEMBL3809067) Show SMILES Cc1cc(C)c(Nc2c(F)cc(F)cc2F)c(C)c1 Show InChI InChI=1S/C15H14F3N/c1-8-4-9(2)14(10(3)5-8)19-15-12(17)6-11(16)7-13(15)18/h4-7,19H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of 8-NBD-cAMP binding to EPAC2 (unknown origin) by microplate reader analysis				ACS Med Chem Lett 7: 460-4 (2016) Article DOI: 10.1021/acsmedchemlett.5b00477 BindingDB Entry DOI: 10.7270/Q2NC6335
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