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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ras guanyl-releasing protein 3' and Ligand = 'BDBM50244479'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ras guanyl-releasing protein 3


(Homo sapiens (Human))		BDBM50244479
PNG
((E)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-3-ylmethy...)
Show SMILES COc1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2cnc3ccccc3c2)C(=O)O1
Show InChI InChI=1S/C24H21NO6/c1-29-20-8-6-17(7-9-20)22(27)30-15-24(14-26)12-19(23(28)31-24)11-16-10-18-4-2-3-5-21(18)25-13-16/h2-11,13,26H,12,14-15H2,1H3/b19-11+
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PC cid
PC sid
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Similars
Article
PubMed
 17n/an/an/an/an/an/an/an/a



National Cancer Institute at Frederick

Curated by ChEMBL


Assay Description
Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells

J Med Chem 51: 5371-86 (2008)


Article DOI: 10.1021/jm800380b
BindingDB Entry DOI: 10.7270/Q21V5DSQ
More data for this
Ligand-Target Pair