Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RecQ-like DNA helicase BLM' and Ligand = 'BDBM50544287'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RecQ-like DNA helicase BLM (Homo sapiens (Human))	BDBM50544287 (CHEMBL4648936) Show SMILES CCN(CC)CCNc1cc2nc(\C=C\c3ccc(cc3)C(C)C)n(C)c(=O)c2cc1F Show InChI InChI=1S/C26H33FN4O/c1-6-31(7-2)15-14-28-24-17-23-21(16-22(24)27)26(32)30(5)25(29-23)13-10-19-8-11-20(12-9-19)18(3)4/h8-13,16-18,28H,6-7,14-15H2,1-5H3/b13-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of His-tagged BLM (642 to 1296 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in DNA unwi...				J Med Chem 63: 9752-9772 (2020) Article DOI: 10.1021/acs.jmedchem.0c00917 BindingDB Entry DOI: 10.7270/Q2CN77GD
					More data for this Ligand-Target Pair