Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RecQ-like DNA helicase BLM' and Ligand = 'BDBM50544289'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RecQ-like DNA helicase BLM (Homo sapiens (Human))	BDBM50544289 (CHEMBL4647563) Show SMILES CCN(CC)CCCNc1cc2nc(\C=C\c3ccc(cc3)C(C)C)n(CC)c(=O)c2cc1F Show InChI InChI=1S/C28H37FN4O/c1-6-32(7-2)17-9-16-30-26-19-25-23(18-24(26)29)28(34)33(8-3)27(31-25)15-12-21-10-13-22(14-11-21)20(4)5/h10-15,18-20,30H,6-9,16-17H2,1-5H3/b15-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of His-tagged BLM (642 to 1296 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in DNA unwi...				J Med Chem 63: 9752-9772 (2020) Article DOI: 10.1021/acs.jmedchem.0c00917 BindingDB Entry DOI: 10.7270/Q2CN77GD
					More data for this Ligand-Target Pair