Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Receptor tyrosine-protein kinase erbB-3' and Ligand = 'BDBM373712'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor tyrosine-protein kinase erbB-3 (Homo sapiens (Human))	BDBM373712 (US10246444, Example 92) Show SMILES OC[C@H](O)COc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)CC1CSSC1 |r| Show InChI InChI=1S/C31H28ClFN4O5S2/c32-25-8-22(4-5-28(25)41-14-18-2-1-3-21(33)6-18)36-31-20(11-34)12-35-26-10-29(42-15-23(39)13-38)27(9-24(26)31)37-30(40)7-19-16-43-44-17-19/h1-6,8-10,12,19,23,38-39H,7,13-17H2,(H,35,36)(H,37,40)/t23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a
Sabila Biosciences LLC Curated by ChEMBL					Assay Description Inhibition of recombinant human wild type partial length HER3 (684 to 987 residues) expressed in mammalian expression system by competitive binding a...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127288 BindingDB Entry DOI: 10.7270/Q2M90D7D
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