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Found 1 hit Enz. Inhib. hit(s) with Target = 'Receptor tyrosine-protein kinase erbB-3' and Ligand = 'BDBM50467163'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Receptor tyrosine-protein kinase erbB-3


(Homo sapiens (Human))		BDBM50467163
PNG
(CHEMBL4290750)
Show SMILES CCOC(=O)c1ccc(Nc2cc(NC(=O)CCCC(O)=O)ncn2)cc1
Show InChI InChI=1S/C18H20N4O5/c1-2-27-18(26)12-6-8-13(9-7-12)21-14-10-15(20-11-19-14)22-16(23)4-3-5-17(24)25/h6-11H,2-5H2,1H3,(H,24,25)(H2,19,20,21,22,23)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 69n/an/an/an/an/an/a



Wenzhou Medical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...

Eur J Med Chem 157: 1300-1325 (2018)


Article DOI: 10.1016/j.ejmech.2018.08.031
BindingDB Entry DOI: 10.7270/Q2SF2ZVS
More data for this
Ligand-Target Pair