Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Receptor-interacting serine/threonine-protein kinase 1' and Ligand = 'BDBM356364'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM356364 (US10604535, Example 112 | US9815850, Compound 112) Show SMILES C[C@H]1Oc2cccnc2N(C)C(=O)[C@H]1NC(=O)c1cc(Cc2ccccc2)on1 |r| Show InChI InChI=1S/C21H20N4O4/c1-13-18(21(27)25(2)19-17(28-13)9-6-10-22-19)23-20(26)16-12-15(29-24-16)11-14-7-4-3-5-8-14/h3-10,12-13,18H,11H2,1-2H3,(H,23,26)/t13-,18+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapeutics Inc. US Patent					Assay Description Assay was performed in polystyrene low volume 384-well black plate, at Room Temperature (RT) in a final volume of 10.1 μl/well using 10 nM of GS...				US Patent US9815850 (2017) BindingDB Entry DOI: 10.7270/Q2W0987J
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM356364 (US10604535, Example 112 | US9815850, Compound 112) Show SMILES C[C@H]1Oc2cccnc2N(C)C(=O)[C@H]1NC(=O)c1cc(Cc2ccccc2)on1 |r| Show InChI InChI=1S/C21H20N4O4/c1-13-18(21(27)25(2)19-17(28-13)9-6-10-22-19)23-20(26)16-12-15(29-24-16)11-14-7-4-3-5-8-14/h3-10,12-13,18H,11H2,1-2H3,(H,23,26)/t13-,18+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapeutics Inc. US Patent					Assay Description Fluorescent polarization binding assay was performed in polystyrene low volume 384-well black plate, at Room Temperature (RT) in a final volume of 10...				US Patent US10604535 (2020) BindingDB Entry DOI: 10.7270/Q2VD72G8
					More data for this Ligand-Target Pair