Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Receptor-interacting serine/threonine-protein kinase 1' and Ligand = 'BDBM50229513'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50229513 (CHEMBL4092903) Show SMILES CCC(C)(C)C(=O)N(C)Cc1ccn(C)n1 Show InChI InChI=1S/C12H21N3O/c1-6-12(2,3)11(16)14(4)9-10-7-8-15(5)13-10/h7-8H,6,9H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
National Institute of Biological Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1 in human HT-29 cells assessed as reduction in TNFalpha/z-VAD-FMK-induced necrosis after 24 hrs by Cell Titer-Glo luminescent cell ...				J Med Chem 60: 972-986 (2017) Article DOI: 10.1021/acs.jmedchem.6b01196 BindingDB Entry DOI: 10.7270/Q2QC05QD
					More data for this Ligand-Target Pair