Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Receptor-interacting serine/threonine-protein kinase 1' and Ligand = 'BDBM50263099'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-interacting serine/threonine-protein kinase 1 (Mus musculus)	BDBM50263099 (CHEMBL4084466) Show SMILES Cc1cc(Nc2nc(Sc3ccc(NC(=O)C4CCCCC4)cc3)nc(n2)N2CCOCC2)n[nH]1 Show InChI InChI=1S/C24H30N8O2S/c1-16-15-20(31-30-16)26-22-27-23(32-11-13-34-14-12-32)29-24(28-22)35-19-9-7-18(8-10-19)25-21(33)17-5-3-2-4-6-17/h7-10,15,17H,2-6,11-14H2,1H3,(H,25,33)(H2,26,27,28,29,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry , University of Antwerp , Universiteitsplein 1 , Wilrijk-Antwerp 2610 , Belgium. Curated by ChEMBL					Assay Description Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 24 hrs followed...				J Med Chem 61: 1895-1920 (2018) Article DOI: 10.1021/acs.jmedchem.7b01449 BindingDB Entry DOI: 10.7270/Q2930WNQ
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Mus musculus)	BDBM50263099 (CHEMBL4084466) Show SMILES Cc1cc(Nc2nc(Sc3ccc(NC(=O)C4CCCCC4)cc3)nc(n2)N2CCOCC2)n[nH]1 Show InChI InChI=1S/C24H30N8O2S/c1-16-15-20(31-30-16)26-22-27-23(32-11-13-34-14-12-32)29-24(28-22)35-19-9-7-18(8-10-19)25-21(33)17-5-3-2-4-6-17/h7-10,15,17H,2-6,11-14H2,1H3,(H,25,33)(H2,26,27,28,29,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry , University of Antwerp , Universiteitsplein 1 , Wilrijk-Antwerp 2610 , Belgium. Curated by ChEMBL					Assay Description Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...				J Med Chem 61: 1895-1920 (2018) Article DOI: 10.1021/acs.jmedchem.7b01449 BindingDB Entry DOI: 10.7270/Q2930WNQ
					More data for this Ligand-Target Pair