Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Receptor-interacting serine/threonine-protein kinase 2' and Ligand = 'BDBM303843'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM303843 (US10138241, Example 29 | US11130754, Example 29) Show SMILES Cc1ccc(cc1-c1cnn(c1)-c1cnn2ccc(cc12)S(=O)(=O)C(C)(C)C)C(=O)NC1CC1 Show InChI InChI=1S/C25H27N5O3S/c1-16-5-6-17(24(31)28-19-7-8-19)11-21(16)18-13-26-30(15-18)23-14-27-29-10-9-20(12-22(23)29)34(32,33)25(2,3)4/h5-6,9-15,19H,7-8H2,1-4H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Method: In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2M61PD9
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM303843 (US10138241, Example 29 | US11130754, Example 29) Show SMILES Cc1ccc(cc1-c1cnn(c1)-c1cnn2ccc(cc12)S(=O)(=O)C(C)(C)C)C(=O)NC1CC1 Show InChI InChI=1S/C25H27N5O3S/c1-16-5-6-17(24(31)28-19-7-8-19)11-21(16)18-13-26-30(15-18)23-14-27-29-10-9-20(12-22(23)29)34(32,33)25(2,3)4/h5-6,9-15,19H,7-8H2,1-4H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...				US Patent US10138241 (2018) BindingDB Entry DOI: 10.7270/Q2VM4FBZ
					More data for this Ligand-Target Pair