Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Receptor-interacting serine/threonine-protein kinase 2' and Ligand = 'BDBM372171'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372171 (N-((tetrahydro- 2H-pyran-4-yl) methyl)-6- (o-tolyl...) Show SMILES Cc1ccccc1-c1cc2nc(NCC3CCOCC3)ncc2[nH]1 Show InChI InChI=1S/C19H22N4O/c1-13-4-2-3-5-15(13)16-10-17-18(22-16)12-21-19(23-17)20-11-14-6-8-24-9-7-14/h2-5,10,12,14,22H,6-9,11H2,1H3,(H,20,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
UNIVERSITY HEALTH NETWORK US Patent					Assay Description Active RIPK2 was purchased from Life Technologies as His-tagged of catalytic domain (amin acids 1-299) of human RIPK2 kinase expressed in insect cell...				US Patent US10875863 (2020) BindingDB Entry DOI: 10.7270/Q2542RPC
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372171 (N-((tetrahydro- 2H-pyran-4-yl) methyl)-6- (o-tolyl...) Show SMILES Cc1ccccc1-c1cc2nc(NCC3CCOCC3)ncc2[nH]1 Show InChI InChI=1S/C19H22N4O/c1-13-4-2-3-5-15(13)16-10-17-18(22-16)12-21-19(23-17)20-11-14-6-8-24-9-7-14/h2-5,10,12,14,22H,6-9,11H2,1H3,(H,20,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair