Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Receptor-interacting serine/threonine-protein kinase 3' and Ligand = 'BDBM392836'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-interacting serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM392836 (US10301306, Example 34) Show SMILES Fc1ccc(cc1)-c1c2c(CCNC2=O)n(Cc2ccc(F)cc2C#N)c1-c1ccncc1 Show InChI InChI=1S/C26H18F2N4O/c27-20-4-1-16(2-5-20)23-24-22(9-12-31-26(24)33)32(25(23)17-7-10-30-11-8-17)15-18-3-6-21(28)13-19(18)14-29/h1-8,10-11,13H,9,12,15H2,(H,31,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The assays were performed in black 1536-well plates. The final assay volume of 2 μl contained a mixture of a fluorescently labeled HTRF probe, T...				Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2M90C19
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