Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein kinase FLT3' and Ligand = 'BDBM174939'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM174939 (US9096593, P-2034) Show SMILES COc1cnc2[nH]cc(Cc3ccc(NCc4ccccc4Cl)nc3F)c2c1 Show InChI InChI=1S/C21H18ClFN4O/c1-28-16-9-17-15(11-25-21(17)26-12-16)8-13-6-7-19(27-20(13)23)24-10-14-4-2-3-5-18(14)22/h2-7,9,11-12H,8,10H2,1H3,(H,24,27)(H,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	25
Plexxikon Inc. US Patent					Assay Description In one assay the biochemical activity IC50 values are determined with respect to inhibition of Flt-3 kinase activity, where inhibition of phosphoryla...				US Patent US9096593 (2015) BindingDB Entry DOI: 10.7270/Q2PK0DXR
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