Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM239010 (US10028934, Compound 7 | US10478423, Cpd. 7 | US94...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 249 | n/a | n/a | n/a | n/a | 7.9 | n/a |
NERVIANO MEDICAL SCIENCES S.R.L. US Patent | Assay Description i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p... | US Patent US10028934 (2018) BindingDB Entry DOI: 10.7270/Q27D2X53 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM239010 (US10028934, Compound 7 | US10478423, Cpd. 7 | US94...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 249 | n/a | n/a | n/a | n/a | n/a | n/a |
NERVIANO MEDICAL SCIENCES S.R.L. US Patent | Assay Description i. Enzyme—The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p... | US Patent US10478423 (2019) BindingDB Entry DOI: 10.7270/Q2WQ065N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM239010 (US10028934, Compound 7 | US10478423, Cpd. 7 | US94...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 249 | n/a | n/a | n/a | n/a | n/a | n/a |
NERVIANO MEDICAL SCIENCES S.R.L. US Patent | Assay Description i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p... | US Patent US9597317 (2017) BindingDB Entry DOI: 10.7270/Q2N58PDX | |||||||||||
More data for this Ligand-Target Pair |