Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM50059889 ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.180 | n/a | n/a | n/a | n/a | n/a | n/a |
Carna Biosciences, Inc. Curated by ChEMBL | Assay Description Inhibition of FLT3 by colorimetric analysis | Bioorg Med Chem Lett 22: 591-6 (2011) Article DOI: 10.1016/j.bmcl.2011.10.076 BindingDB Entry DOI: 10.7270/Q2JQ11GW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM50059889 ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a |
Califia Bio Inc. Curated by ChEMBL | Assay Description Binding affinity to human FLT3 | J Med Chem 56: 8032-48 (2013) Article DOI: 10.1021/jm401094t BindingDB Entry DOI: 10.7270/Q2P270KS | |||||||||||
More data for this Ligand-Target Pair |