Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein kinase FLT3' and Ligand = 'BDBM50177721'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50177721 (CHEMBL3814657) Show SMILES CN(C)CCCn1cc(cn1)-c1ccc2C(=O)c3c([nH]c4cc(ccc34)C#N)-c2c1 Show InChI InChI=1S/C24H21N5O/c1-28(2)8-3-9-29-14-17(13-26-29)16-5-7-18-20(11-16)23-22(24(18)30)19-6-4-15(12-25)10-21(19)27-23/h4-7,10-11,13-14,27H,3,8-9H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of FLT3 ITD mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer glo...				ACS Med Chem Lett 7: 476-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00498 BindingDB Entry DOI: 10.7270/Q2HD7XJD
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50177721 (CHEMBL3814657) Show SMILES CN(C)CCCn1cc(cn1)-c1ccc2C(=O)c3c([nH]c4cc(ccc34)C#N)-c2c1 Show InChI InChI=1S/C24H21N5O/c1-28(2)8-3-9-29-14-17(13-26-29)16-5-7-18-20(11-16)23-22(24(18)30)19-6-4-15(12-25)10-21(19)27-23/h4-7,10-11,13-14,27H,3,8-9H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of FLT3 D835Y mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer g...				ACS Med Chem Lett 7: 476-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00498 BindingDB Entry DOI: 10.7270/Q2HD7XJD
					More data for this Ligand-Target Pair