Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein kinase FLT3' and Ligand = 'BDBM50185415'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50185415 (CHEMBL3823520) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4cn(nn4)-c4ccccc4Cl)cc3F)ccnc2cc1OCCCN1CCCCC1 Show InChI InChI=1S/C33H32ClFN6O4/c1-43-31-19-23-26(20-32(31)44-17-7-16-40-14-5-2-6-15-40)36-13-12-29(23)45-30-11-10-22(18-25(30)35)37-33(42)27-21-41(39-38-27)28-9-4-3-8-24(28)34/h3-4,8-13,18-21H,2,5-7,14-17H2,1H3,(H,37,42)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of FLT3 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 30 mins by HTRF assay				Eur J Med Chem 119: 96-108 (2016) Article DOI: 10.1016/j.ejmech.2016.04.035 BindingDB Entry DOI: 10.7270/Q24J0H2G
					More data for this Ligand-Target Pair