Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein kinase FLT3' and Ligand = 'BDBM50217353'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50217353 ((E)-4-(6-amino-5-((2-morpholino-2-oxoethoxyimino)m...) Show SMILES CC(C)Oc1ccc(NC(=O)N2CCN(CC2)c2ncnc(N)c2\C=N\OCC(=O)N2CCOCC2)cc1 Show InChI InChI=1S/C25H34N8O5/c1-18(2)38-20-5-3-19(4-6-20)30-25(35)33-9-7-32(8-10-33)24-21(23(26)27-17-28-24)15-29-37-16-22(34)31-11-13-36-14-12-31/h3-6,15,17-18H,7-14,16H2,1-2H3,(H,30,35)(H2,26,27,28)/b29-15+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Inhibition of human FLT3				Bioorg Med Chem Lett 17: 4861-5 (2007) Article DOI: 10.1016/j.bmcl.2007.06.046 BindingDB Entry DOI: 10.7270/Q2T72H47
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