Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein kinase FLT3' and Ligand = 'BDBM50521490'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50521490 (CHEMBL4454804) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(cc2F)-c2cn(CC=C)c3ncnc(N)c23)no1 Show InChI InChI=1S/C23H24FN7O2/c1-5-8-31-11-14(19-20(25)26-12-27-21(19)31)13-6-7-16(15(24)9-13)28-22(32)29-18-10-17(33-30-18)23(2,3)4/h5-7,9-12H,1,8H2,2-4H3,(H2,25,26,27)(H2,28,29,30,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...				J Med Chem 62: 4158-4173 (2019) Article DOI: 10.1021/acs.jmedchem.9b00223 BindingDB Entry DOI: 10.7270/Q2QJ7MPQ
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