Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein kinase FLT3' and Ligand = 'BDBM50523921'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50523921 (CHEMBL4446992) Show SMILES COc1cc2c(Oc3ccc(cc3F)C3SCC(=O)N3NC(=O)Nc3ccc(F)cc3F)ccnc2cc1OCCCN1CCN(C)CC1 Show InChI InChI=1S/C34H35F3N6O5S/c1-41-11-13-42(14-12-41)10-3-15-47-31-19-27-23(18-30(31)46-2)28(8-9-38-27)48-29-7-4-21(16-25(29)37)33-43(32(44)20-49-33)40-34(45)39-26-6-5-22(35)17-24(26)36/h4-9,16-19,33H,3,10-15,20H2,1-2H3,(H2,39,40,45)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
Zhuhai Campus of Zunyi Medical University Curated by ChEMBL					Assay Description Inhibition of FLT3 (unknown origin) using FAM-labelled peptide as substrate measured after 10 mins by mobility shift assay				Bioorg Med Chem 27: 2127-2139 (2019) Article DOI: 10.1016/j.bmc.2019.03.049 BindingDB Entry DOI: 10.7270/Q27P92TP
					More data for this Ligand-Target Pair