Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein kinase FLT3 [564-993]' and Ligand = 'BDBM239036'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 [564-993] (Homo sapiens (Human))	BDBM239036 (US10028934, Compound 25 | US10478423, Cpd. 25 | US...) Show SMILES O=C(Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12)c1ccc(NCCN2CCOCC2)cc1 Show InChI InChI=1S/C29H33N5O4/c35-29(23-6-8-24(9-7-23)30-12-13-34-14-16-36-17-15-34)31-28-26-11-10-25(20-27(26)32-33-28)38-19-18-37-21-22-4-2-1-3-5-22/h1-11,20,30H,12-19,21H2,(H2,31,32,33,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	74	n/a	n/a	n/a	n/a	7.9	28
NERVIANO MEDICAL SCIENCES S.R.L. US Patent					Assay Description The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was pre activat...				US Patent US9408850 (2016) BindingDB Entry DOI: 10.7270/Q2F47N2F
					More data for this Ligand-Target Pair