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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein phosphatase C' and Ligand = 'BDBM50099757'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Receptor-type tyrosine-protein phosphatase C


(Homo sapiens (Human))		BDBM50099757
PNG
(4-(Carboxymethyl-carbamoyl)-4-{[1-(2-{2-[(9,10-dio...)
Show SMILES NC(=N)NCCCC(NC(=O)c1ccc2-c3ccccc3C(=O)C(=O)c2c1)C(=O)NC(CCCNC(N)=N)C(=O)N1CCCC1C(=O)NC(CCC(O)=O)C(=O)NCC(O)=O
Show InChI InChI=1S/C39H49N11O11/c40-38(41)44-15-3-8-25(47-33(57)20-11-12-22-21-6-1-2-7-23(21)31(55)32(56)24(22)18-20)35(59)49-27(9-4-16-45-39(42)43)37(61)50-17-5-10-28(50)36(60)48-26(13-14-29(51)52)34(58)46-19-30(53)54/h1-2,6-7,11-12,18,25-28H,3-5,8-10,13-17,19H2,(H,46,58)(H,47,57)(H,48,60)(H,49,59)(H,51,52)(H,53,54)(H4,40,41,44)(H4,42,43,45)
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AstraZeneca Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against the cytosolic portion of CD45 protein-tyrosine phosphatase using pNPP as the substrate

J Med Chem 44: 1777-93 (2001)


BindingDB Entry DOI: 10.7270/Q2X34WQQ
More data for this
Ligand-Target Pair