Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein phosphatase beta' and Ligand = 'BDBM359100'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein phosphatase beta (Homo sapiens (Human))	BDBM359100 (US10220048, Compound AA10 | US10952992, No. AA10 |...) Show SMILES COC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(NS(O)(=O)=O)cc1)c1nc(cs1)C(C)(C)C |r| Show InChI InChI=1S/C26H32N4O6S2/c1-26(2,3)22-16-37-24(29-22)21(15-18-10-12-19(13-11-18)30-38(33,34)35)27-23(31)20(28-25(32)36-4)14-17-8-6-5-7-9-17/h5-13,16,20-21,30H,14-15H2,1-4H3,(H,27,31)(H,28,32)(H,33,34,35)/t20-,21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
AERPIO THERAPEUTICS, INC. US Patent					Assay Description HPTP-β inhibition can be tested by any method chosen by the formulator, for example, Amarasinge K. K. et al., “Design and Synthesis of Potent, N...				US Patent US10220048 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VC9
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase beta (Homo sapiens (Human))	BDBM359100 (US10220048, Compound AA10 | US10952992, No. AA10 |...) Show SMILES COC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(NS(O)(=O)=O)cc1)c1nc(cs1)C(C)(C)C |r| Show InChI InChI=1S/C26H32N4O6S2/c1-26(2,3)22-16-37-24(29-22)21(15-18-10-12-19(13-11-18)30-38(33,34)35)27-23(31)20(28-25(32)36-4)14-17-8-6-5-7-9-17/h5-13,16,20-21,30H,14-15H2,1-4H3,(H,27,31)(H,28,32)(H,33,34,35)/t20-,21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem		n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2RV0SPJ
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase beta (Homo sapiens (Human))	BDBM359100 (US10220048, Compound AA10 | US10952992, No. AA10 |...) Show SMILES COC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(NS(O)(=O)=O)cc1)c1nc(cs1)C(C)(C)C |r| Show InChI InChI=1S/C26H32N4O6S2/c1-26(2,3)22-16-37-24(29-22)21(15-18-10-12-19(13-11-18)30-38(33,34)35)27-23(31)20(28-25(32)36-4)14-17-8-6-5-7-9-17/h5-13,16,20-21,30H,14-15H2,1-4H3,(H,27,31)(H,28,32)(H,33,34,35)/t20-,21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Non-limiting examples of the HPTPβ IC50 (μM) activity.				Citation and Details BindingDB Entry DOI: 10.7270/Q2668HD5
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase beta (Homo sapiens (Human))	BDBM359100 (US10220048, Compound AA10 | US10952992, No. AA10 |...) Show SMILES COC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(NS(O)(=O)=O)cc1)c1nc(cs1)C(C)(C)C |r| Show InChI InChI=1S/C26H32N4O6S2/c1-26(2,3)22-16-37-24(29-22)21(15-18-10-12-19(13-11-18)30-38(33,34)35)27-23(31)20(28-25(32)36-4)14-17-8-6-5-7-9-17/h5-13,16,20-21,30H,14-15H2,1-4H3,(H,27,31)(H,28,32)(H,33,34,35)/t20-,21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
AERPIO PHARMACEUTICALS, INC. US Patent					Assay Description Non-limiting examples of the HPTP-β IC50 (μM) activity.				US Patent US10952992 (2021) BindingDB Entry DOI: 10.7270/Q2FR00R3
					More data for this Ligand-Target Pair