Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Renin' and Ligand = 'BDBM50025943'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Renin (Homo sapiens (Human))	BDBM50025943 (3-Hydroxy-4-[3-(1H-imidazol-4-yl)-2-(2-phenoxy-ace...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)COc1ccccc1)[C@@H](O)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r| Show InChI InChI=1S/C37H51N7O7/c1-23(2)15-28(43-37(50)31(18-26-20-39-22-40-26)42-34(47)21-51-27-13-9-6-10-14-27)32(45)19-33(46)41-30(16-24(3)4)36(49)44-29(35(38)48)17-25-11-7-5-8-12-25/h5-14,20,22-24,28-32,45H,15-19,21H2,1-4H3,(H2,38,48)(H,39,40)(H,41,46)(H,42,47)(H,43,50)(H,44,49)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human kidney renin				J Med Chem 28: 1779-90 (1986) BindingDB Entry DOI: 10.7270/Q2FJ2HC2
					More data for this Ligand-Target Pair