BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Renin' and Ligand = 'BDBM50046796'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Renin (Homo sapiens (Human))	BDBM50046796 ((S)-N-[(S)-1-((1S,2R,3S)-1-Cyclohexylmethyl-2,3-di...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.870	n/a	n/a	n/a	n/a	7.4	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of human plasma renin at PH 7.4				Bioorg Med Chem Lett 2: 1405-1410 (1992) Article DOI: 10.1016/S0960-894X(00)80522-3 BindingDB Entry DOI: 10.7270/Q2VD6ZBV
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Renin (Homo sapiens (Human))	BDBM50046796 ((S)-N-[(S)-1-((1S,2R,3S)-1-Cyclohexylmethyl-2,3-di...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.870	n/a	n/a	n/a	n/a	7.4	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against human plasma renin at pH 7.4				J Med Chem 36: 460-7 (1993) BindingDB Entry DOI: 10.7270/Q2VT1R5C
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair