BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Renin' and Ligand = 'BDBM50350914'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Renin


(Homo sapiens (Human))		BDBM50350914
PNG
(CHEMBL1818071)
Show SMILES COCCCC[C@](O)([C@H]1CN(CCO1)C(=O)[C@H]1C[C@@H](N)[C@@H](O)C1)c1cccc(Cl)c1-c1cccc(SC)c1 |r|
Show InChI InChI=1S/C29H39ClN2O5S/c1-36-13-4-3-11-29(35,22-9-6-10-23(30)27(22)19-7-5-8-21(15-19)38-2)26-18-32(12-14-37-26)28(34)20-16-24(31)25(33)17-20/h5-10,15,20,24-26,33,35H,3-4,11-14,16-18,31H2,1-2H3/t20-,24+,25-,26+,29+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 2.30n/an/an/an/an/an/a



USA.

Curated by ChEMBL


Assay Description
Inhibition of recombinant human renin using of DABCYL-c-Abu-IleHis-Pro-Phe-His-Leu-Val-Ile-His-Thr-EDANS as substrate after 60 to 360 mins by fluores...

Bioorg Med Chem Lett 21: 4836-43 (2011)


Article DOI: 10.1016/j.bmcl.2011.06.043
BindingDB Entry DOI: 10.7270/Q25M663G
More data for this
Ligand-Target Pair