Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Replication protein A 70 kDa DNA-binding subunit' and Ligand = 'BDBM461272'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM461272 (US10774063, Compound f) Show SMILES COc1ccc2cc(C3CC(=NN3C(=O)CCC(O)=O)c3ccc(Cl)cc3)c(Cl)nc2c1 |c:10| Show InChI InChI=1S/C23H19Cl2N3O4/c1-32-16-7-4-14-10-17(23(25)26-18(14)11-16)20-12-19(13-2-5-15(24)6-3-13)27-28(20)21(29)8-9-22(30)31/h2-7,10-11,20H,8-9,12H2,1H3,(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University Research and Technology Corporation US Patent					Assay Description EMSA reactions (20 μL) were performed with 50 nM fl-RPA and 2.5 nM 5′[32P]-labeled 34-base DNA in buffer containing 20 mM HEPES (pH 7.0), ...				US Patent US10774063 (2020) BindingDB Entry DOI: 10.7270/Q21N8479
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