Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Replication protein A 70 kDa DNA-binding subunit' and Ligand = 'BDBM50437312'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM50437312 (CHEMBL2407593) Show SMILES OC(=O)CSc1nnc(-c2sc3ccccc3c2Cl)n1-c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C18H10Cl3N3O2S2/c19-11-6-5-9(7-12(11)20)24-17(22-23-18(24)27-8-14(25)26)16-15(21)10-3-1-2-4-13(10)28-16/h1-7H,8H2,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human RPA70N assessed as inhibition of interaction with FITC-Ahx-DFTADDLEELDTLAS-NH2 after 1 hr by fluorescence polarization anis...				ACS Med Chem Lett 4: 601-605 (2013) Article DOI: 10.1021/ml400032y BindingDB Entry DOI: 10.7270/Q22N53PW
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