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Found 1 hit Enz. Inhib. hit(s) with Target = 'Replication protein A 70 kDa DNA-binding subunit' and Ligand = 'BDBM50437317'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Replication protein A 70 kDa DNA-binding subunit


(Homo sapiens (Human))		BDBM50437317
PNG
(CHEMBL2407467)
Show SMILES OC(=O)c1sc2cc(ccc2c1Cl)-n1c(n[nH]c1=S)C1CCCCC1
Show InChI InChI=1S/C17H16ClN3O2S2/c18-13-11-7-6-10(8-12(11)25-14(13)16(22)23)21-15(19-20-17(21)24)9-4-2-1-3-5-9/h6-9H,1-5H2,(H,20,24)(H,22,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 2.50E+4n/an/an/an/an/a



Vanderbilt University School of Medicine

Curated by ChEMBL


Assay Description
Binding affinity to human RPA70N assessed as inhibition of interaction with FITC-Ahx-DFTADDLEELDTLAS-NH2 after 1 hr by fluorescence polarization anis...

ACS Med Chem Lett 4: 601-605 (2013)


Article DOI: 10.1021/ml400032y
BindingDB Entry DOI: 10.7270/Q22N53PW
More data for this
Ligand-Target Pair