Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Replicative DNA helicase' and Ligand = 'BDBM50179001'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Replicative DNA helicase (Pseudomonas aeruginosa)	BDBM50179001 (CHEMBL204761 | N2,N4-bis(3,4-difluorophenyl)-6-(4-...) Show SMILES CC(C)CN1CCN(CC1)c1nc(Nc2ccc(F)c(F)c2)nc(Nc2ccc(F)c(F)c2)n1 Show InChI InChI=1S/C23H25F4N7/c1-14(2)13-33-7-9-34(10-8-33)23-31-21(28-15-3-5-17(24)19(26)11-15)30-22(32-23)29-16-4-6-18(25)20(27)12-16/h3-6,11-12,14H,7-10,13H2,1-2H3,(H2,28,29,30,31,32)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Targanta Therapeutics Inc. Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa DnaB helicase				Bioorg Med Chem Lett 16: 1286-90 (2006) Article DOI: 10.1016/j.bmcl.2005.11.076 BindingDB Entry DOI: 10.7270/Q2PG1R95
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