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Found 1 hit Enz. Inhib. hit(s) with Target = 'Replicative DNA helicase' and Ligand = 'BDBM50400439'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Replicative DNA helicase


(Bacillus anthracis)		BDBM50400439
PNG
(CHEMBL2177802)
Show SMILES Cc1c(OCc2ccc3ccc(Cl)cc3n2)ccc2c(C)c(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C24H20ClNO5/c1-13-18-7-9-21(14(2)23(18)31-24(29)19(13)8-10-22(27)28)30-12-17-6-4-15-3-5-16(25)11-20(15)26-17/h3-7,9,11H,8,10,12H2,1-2H3,(H,27,28)
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 5.60E+4n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay

J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair