Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta' and Ligand = 'BDBM50019847'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019847 (CHEMBL3286913) Show SMILES Cc1nc2ccccc2n1[C@H](COC(=O)C1CCN(CC1)c1nc2ccccc2n1Cc1ccsc1)C1CCNCC1 |r| Show InChI InChI=1S/C33H38N6O2S/c1-23-35-28-7-3-5-9-30(28)39(23)31(25-10-15-34-16-11-25)21-41-32(40)26-12-17-37(18-13-26)33-36-27-6-2-4-8-29(27)38(33)20-24-14-19-42-22-24/h2-9,14,19,22,25-26,31,34H,10-13,15-18,20-21H2,1H3/t31-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair