Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta' and Ligand = 'BDBM50249983'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50249983 (CHEMBL4060010) Show SMILES Fc1ccccc1C1Nc2ccccc2C(=O)N1CCN1CCC(CN2C(Nc3ccccc3C2=O)c2ccccc2F)CC1 Show InChI InChI=1S/C36H35F2N5O2/c37-29-13-5-1-9-25(29)33-39-31-15-7-3-11-27(31)35(44)42(33)22-21-41-19-17-24(18-20-41)23-43-34(26-10-2-6-14-30(26)38)40-32-16-8-4-12-28(32)36(43)45/h1-16,24,33-34,39-40H,17-23H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a
School of Pharmacy, Second Military Medical University , Shanghai 200433, China. Curated by ChEMBL					Assay Description Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay				J Med Chem 60: 9400-9406 (2017) Article DOI: 10.1021/acs.jmedchem.7b01243 BindingDB Entry DOI: 10.7270/Q2571FDQ
					More data for this Ligand-Target Pair