Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50341378 (CHEBI:9921 | Valerenic Acid) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents | n/a | n/a | n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a | |
TBA | Assay Description Antagonist activity at 5-HT3 receptor in guinea pig ileum muscle | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50341378 (CHEBI:9921 | Valerenic Acid) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a |
Swiss Federal Institute of Technology (ETH) Curated by ChEMBL | Assay Description Transactivation of human Gal4-fused RXRalpha LBD expressed in HEK293T cells after 12 to 14 hrs by dual-glo luciferase assay | J Med Chem 61: 5442-5447 (2018) Article DOI: 10.1021/acs.jmedchem.8b00494 BindingDB Entry DOI: 10.7270/Q2J38W5N | |||||||||||
More data for this Ligand-Target Pair |