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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Retinoic acid receptor RXR-alpha' and Ligand = 'BDBM50427895'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50427895
PNG
(CHEMBL2322955)
Show SMILES CNCCCn1c2-c3ccccc3C(=O)c2c2ccccc2c1=O
Show InChI InChI=1S/C20H18N2O2/c1-21-11-6-12-22-18-14-8-3-4-9-15(14)19(23)17(18)13-7-2-5-10-16(13)20(22)24/h2-5,7-10,21H,6,11-12H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 9.22E+3n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay


J Med Chem 56: 2581-605 (2013)


Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG
More data for this
Ligand-Target Pair