Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Retinoic acid receptor RXR-beta' and Ligand = 'BDBM50341381'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoic acid receptor RXR-beta (Homo sapiens (Human))	BDBM50341381 (CHEMBL4171515) Show SMILES Cc1c(C)n(c2CCC(F)(F)Cc12)-c1ccc(CC(O)=O)cc1 Show InChI InChI=1S/C18H19F2NO2/c1-11-12(2)21(16-7-8-18(19,20)10-15(11)16)14-5-3-13(4-6-14)9-17(22)23/h3-6H,7-10H2,1-2H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a
Swiss Federal Institute of Technology (ETH) Curated by ChEMBL					Assay Description Transactivation of human Gal4-fused RXRbeta LBD expressed in HEK293T cells after 12 to 14 hrs by dual-glo luciferase assay				J Med Chem 61: 5442-5447 (2018) Article DOI: 10.1021/acs.jmedchem.8b00494 BindingDB Entry DOI: 10.7270/Q2J38W5N
					More data for this Ligand-Target Pair