Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Reverse transcriptase/RNaseH' and Ligand = 'BDBM50057815'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50057815 (1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-...) Show SMILES COCCOCn1c(=O)c(C)cn(C2CC(N=[N+]=[N-])C(CO)O2)c1=O Show InChI InChI=1S/C14H21N5O6/c1-9-6-18(12-5-10(16-17-15)11(7-20)25-12)14(22)19(13(9)21)8-24-4-3-23-2/h6,10-12,20H,3-5,7-8H2,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40E+5	n/a	n/a	n/a	n/a
Institut de Chimie des Substances Naturelles CNRS Curated by ChEMBL					Assay Description Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.				J Med Chem 40: 1550-8 (1997) Article DOI: 10.1021/jm9600095 BindingDB Entry DOI: 10.7270/Q2TH8KSM
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